DEVELOPMENT AND APPLICATIONS OF A ZEBRAFISH (DANIO RERIO) CYP1A-TARGETED MONOCLONAL ANTIBODY (CRC4) WITH REACTIVITY ACROSS VERTEBRATE TAXA: EVIDENCE FOR A CONSERVED CYP1A EPITOPE

CYP1A is a heme-thiolate enzyme associated with the cytochrome P4501A1 monooxygenase system and is inducible by a wide variety of xenobiotics and endogenous ligands that bind and activate the aryl hydrocarbon receptor (AHR).The AHR-CYP1A axis is important for detoxification of certain xenobiotics and for homeostatic balance of endogenous sex hormon

Candidemia poses a major threat to ICU patients and is routinely diagnosed by blood Raw Superfoods culture, which is known for its low sensitivity and long turnaround times.We compared the performance of a novel, Candida-specific multiplex real-time PCR assay (Fungiplex® Candida IVD Real-Time PCR Kit) with blood culture and another established